Large- Scale Content Based Face Image Retrieval using Attribute Enhanced Sparse Codewords.

Content based image retrieval (CBIR) have turn into majority dynamic exploration regions within previous couple of existence. Numerous index strategies be in light of worldwide component circulations. Be that as it may, these worldwide circulations have restricted segregating force since they are not able to catch nearby picture data. Photographs with individuals are the foremost attention of users. Consequently with exponentially increasing pictures, huge size contented base features representation recovery is a facilitating knowledge in favor of various developing applications. The main objective is to apply automatically spotted human characteristics that comprise semantic cue of facade pictures toward increase gratified base facade recovery through creating semantic codeword pro effectual huge size countenance recovery. With leveraging person characteristics into scalable as well as methodical structure, suggest and offer two orthogonal systems named attribute improved meager code and attribute entrenched upturned index toward develop facade recovery. We compare proposed method with other three methods namely LBP, ATTR and SC methods. The results illustrate that the proposed methods can attain qualified enhancement in Mean Average Precision (MAP) associated to the existing methods. DOI: 10.17762/ijritcc2321-8169.15084

Experimental evaluation of Ardrakadi Ghritam for its Anti-microbial Activity

Background: Ardrakadi Ghrita mentioned in Sahasrayogam and its Anti-microbial activity was analyzed. Aim and objective: An experimental evaluation of Ardrakadi Ghrita for its Anti-microbial activity. Methods: Experimental evaluation of Ardrakadi Ghritam for its Anti-microbial activity against microbes such as Escherichia Coli and Klebsiella Pneumonia. Results: Determination of zone inhibition by Agar well diffusion method. For Test Organism are Escherichia Coli and Klebsiella Pneumonia. Inoculum: Cell suspension prepared from cultures grown on Trypsin broth adjusted to 1-2 x105cells/ml. Conclusion: From the experimental study the result it was found that Ardrakadi Ghrita not showed ant- microbial activity

Surgical outcomes of patients with early cervical cancer treated with radical hysterectomy in a tertiary care hospital

Background: This study was undertaken to evaluate the surgical outcomes of patients with early cervical cancer treated with radical hysterectomy.Methods:  A total of 50 patients who underwent modified radical hysterectomy between April 2006 and April 2016 at Shri Dharmasthala Manjunatheswara medical college and hospital, Dharwad, Karnataka were retrospectively reviewed. The analysis included clinical and pathologic variables including age, tumour size, clinical stage, lymphovascular space involvement, tumour type and grade, lymph node metastases, surgical margin involvement, intraoperative and postoperative complications and pattern of adjuvant therapy were analysed. Results: The median age of the patient who underwent radical hysterectomy was 47.8 years, the mean parity being 3.6. Histologically, the most common type of malignancy encountered was squamous cell carcinoma of the cervix, which occurred in 42 patients (84 %). 8 (16%) showed involvement of 1 or more lymph nodes and evidence of lymphovascular invasion. Involvement of the resected vaginal margins was noted in 11 patients (22%). The average hospital stay was 19.8 days, the prolonged stay resulting from postoperative morbidity. Postoperative concurrent chemoradiation with cisplatin was administered in eight (16%) cases due to pelvic lymph node metastases. Postoperative vaginal brachytherapy was given in 11 (22%) cases because of positive vaginal margins.Conclusions: The present study shows that general gynaecologists with significant experience in general gynaecologic surgery may, with adequate but abbreviated training, become competent in performing a modified radical hysterectomy.

Evaluation of antidepressant effect of aqueous extract of Psidium guajava leaves on Wistar albino rats

Background: Depression is one of the common mental disorder prevalent worldwide. Use of herbal medicines in the treatment of depression is becoming popular because of adverse effects of existing non herbal drugs. In this study Psidium guajava leaf aqueous extract is screened for antidepressant activity in Wistar albino rats.Methods: Wistar albino rats of both sex were used. After performing acute toxicity study, dose of test drug was fixed to 100mg/kg and 200mg/kg. Test and standard drugs were administered for 10 days orally. Standard drug used was Imipramine. Antidepressant activity was assessed using forced swim test and tail suspension test.Results: Statistical analysis was done by one way ANOVA followed by Tukey Kramer. Aqueous extract of Psidium guajava leaves showed significant antidepressant activity. Both Psidium guajava aqueous extract (PGAE)-100mg/kg and 200mg/kg showed antidepressant effect but compared to 100mg/kg dose of PGAE, 200mg/kg showed significant antidepressant activity.Conclusions: From this study it can be concluded that aqueous extract of Psidium guajava leaves has antidepressant activity

Preclinical evaluation of antidepressant activity of aqueous extract of Piper betle leaves in Swiss albino mice

Background: There is a growing demand for alternative medicines derived from indigenous plants having natural antioxidants and neuroprotective actions for the treatment of many behavioural disorders such as anxiety and depression. This study was designed to screen antidepressant activity of aqueous extract of Piper betle L. leaf (betel leaf) in Swiss albino mice.Methods: Swiss albino mice of both sexes weighing 25-30grams were used in the present study. Piper betle leaves aqueous extract (PBAE) was administered to the animals at a dose of 100, 200mg/kg body weight orally for 14 days. On the 14th day, after 1 hour of PBAE administration, experiments on force swim test (FST) and tail suspension (TST) were carried out for studying the level of depression. In FST and TST, time of immobility was noted for a period of 5 minutes.Results: Data was analyzed by one-way ANOVA followed by Tukey Kramer’s multiple comparison test at P = 0.05. The results were represented as Mean±SE. PBAE at a dose of 100mg/kg has shown significant antidepressant activity, as evidenced by decrease in the immobility time in both the screening tests of depression.Conclusions: Present results demonstrated that PBAE possess potent antidepressant property. The exact mechanism(s) related to the active compound(s) in Piper betle leaf extract have to be elucidated in future studies

HLA-A<SUP>∗</SUP>0201-restricted cytotoxic T-cell epitopes in three PE/PPE family proteins of Mycobacterium tuberculosis

CD8+ T cells are thought to play an important role in protective immunity against tuberculosis. We report the identification of three peptides derived from Rv1818c, Rv3812 and Rv3018c proteins of Mycobacterium tuberculosis that bound to HLA-A&#8727;0201 molecules and their ability to induce in vitro T-cell response in peripheral blood lymphocytes from HLA-A&#8727;0201-positive healthy individuals (PPD+) and patients with TB. The peptide-specific cytotoxic T lymphocytes (CTL) generated were capable of recognizing peptide pulsed targets. Three 9-mer peptides bound with high affinity to HLA-A&#8727;0201 and displayed low dissociation rates of the bound peptide from HLA. Epitope-specific recognition was demonstrated by the release of perforin and -interferon. Overall, our results demonstrate the presence of HLA class I-restricted CD8+ CTL against proteins from PE and PPE proteins of M. tuberculosis and identify epitopes that are strongly recognized by HLA-A&#8727;0201-restricted CD8+ T cells in humans. These epitopes thus represent potential subunit components for the design of vaccines against tuberculosis

Prevalence of bacterial vaginosis in females in the reproductive age group in Kadur, Karnataka, India

Background: Bacterial vaginosis, well known as the nonspecific vaginitis is caused by the normal resident flora of the vagina, predominantly by the peroxides producing lactobacillus species, when there is a disparity in their proportion and replaced by Gardinerella vaginalis, Mycoplasm hominis, Mobilunceus species, Bacteroids species, Prevotela species, Fusobacterium species and Porphyromonus species, Peptostreptococcus species.Methods: A cross section study was performed to study the prevalence of bacterial vaginosis in the reproductive age group women and the associated risk factors. The diagnosis of the vaginosis was made from the smear and Amsle’s clinical criteria.Results: Out of 250 patients 112 (44.8%) were diagnosed to have BV, 20-29-year age group had the largest percentage of infection 69 (61.6%). IUCD users 36 (32.14%) are found to be suffering from BV. Vaginal candidiasis, trichomonas vaginalis and atypical cell of unknown significant was seen in 32 (28.5%), 9 (8.03%) and 17 (15.17%) women respectively.Conclusions: A routine high vaginal swab for smear and culture must be performed for every woman presenting with chronic white discharge and itching, to prevent misuse usage of antibiotic. Further studies are needed to study the associated risk factors for BV

Role of Doppler indices of umbilical and middle cerebral artery in prediction of perinatal outcome in preeclampsia

Background: Hypertension which develops de novo in pregnancy appears to be unique to human and continue to be a major cause of reported perinatal mortality. The aim and objectives of the study was to evaluate the diagnostic value of Umbilical and Middle cerebral artery Doppler in predicting the perinatal outcome in preeclampsia.Methods: A prospective study at Sri Siddhartha Medical College and Hospital between October2013-September2015 on 80pregnant women with preeclampsia at &gt;30weeks gestation. Studies of fetal vessels were performed using a pulsed Doppler ultrasound. Resistance Index (RI), Pulsatility Index (PI) and systolic/diastolic ratio (S/D) were measured in umbilical artery (UA) and Middle cerebral artery (MCA) and perinatal outcomes were monitored and statistically analyzed.Results: Out of 80 cases studied, 25 cases showed adverse perinatal outcome, among which 6 cases with perinatal death, 13 cases had low APGAR at 5minutes. 6 cases had NICU admission.Conclusions: Color Doppler has an important role in antepartum fetal surveillance in preeclampsia which can detect fetal compromise at an early stage. In our study pulsatility index of umbilical artery and ratio of MCA/UA PI was more sensitive than other parameters with PPV 78%

A prospective study of effect of amniotic fluid index less than 5 at term on perinatal outcome

Background: To study the effect of oligohydramnios in pregnancy and its value in predicting adverse perinatal outcome.Methods: A prospective case control study of pregnancy outcome in 100 cases with ultrasound diagnosis of oligohydramnios at term compared with 100 controls with no oligohydramnios. The study was done over a period of 3 years at SSMC Tumkur, India.Results: Oligohydramnios at term is associated with poor perinatal outcome. Significant increase in abnormal foetal heart rate, meconium stained liquor, delivery by cesarean section, low Apgar intrauterine growth restriction (IUGR), increased admissions to  neonatal intensive-care unit (NICU) were seen in study group, however perinatal mortality was more in study group but not statistically significant (P=0.31)Conclusions: AFI <5 at term is an important fetal surveillance methods to identify poor perinatal outcome and thereby makes possible intervention so as to reduce perinatal morbidity and mortality

Ashoka [Saraca Asoca (Roxb.) Willd.] : A Salubrious Plant

Over the centuries, plants have been known to be a potential source of therapeutics. A comprehensive review of medicinal plants and its diversified action in mitigating the diseases is essential to be documented for serving mankind. Saraca asoca (Roxb.) willd. Belonging to the family Caesalpinioideae is a rain-forest tree, prized for its beautiful foliage and fragrant flowers. It’s found wild along streams and in the shades of evergreen forests. All most all parts of the plant are considered as pharmacologically important especially bark and flower. Bark is generally adulterated part of the plant with the bark of other plants like Polyalthia longifolia, Bauhinia variegata and Shorea robusta. It mainly contains tannin and catechin in substantial amount and widely used as uterine tonic, Antimenorrhagia, Analgesic, Anti-pyretic, Anthelmintic, Dermatoprotective and anti-diabetic. The current article highlights about review of Ashoka and its microscopical features